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Disease and Chemical Links

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Disease	1st cat.	2nd cat.	3rd cat.	Strong Evidence	Good Evidence	Limited Evidence	Notes	References and Footnotes
Trigeminal neuropathy	Neuro				Dichloroacetylene	Trichloroethylene (TCE)
Vinyl chloride disease, Acro-osteolysis	Autoimm	Derm		Vinyl chloride			Affected workers polymerizing vinyl c...
Vasculitis	Autoimm	C.V.			Silica	Solvents, Pesticides, Welding fumes	Includes primary systemic vasculitis,...	77, 97
Vaginal cancer	Onc	G.U.	Female	DES
Uterine cancer	Onc	G.U.	Female			Estrogens, Ethylene oxide, Pesticides...		30, 131
Undifferentiated Connective Tissue Di...	Autoimm	Female			Solvents (including paint thinners/re...		Solvents exposure from paint thinners...	10, 77
Wilm's Tumor	Onc	Renal	Peds.			Aromatic amines, Lead, Pesticides	Parental occupational exposure has be...	35, 36
Silicosis	Resp			Silica			Silicosis is associate with an increa...
Skin cancer (non-melanoma)	Onc	Derm		Arsenic+, Coal tar+, Ionizing radiati...	Aromatic amines, Creosotes#, Ethylene...	Acrylamide^, Vinyl chloride	+ - Group 1 human carcinogen (IARC); ...	11, 98
Skin ulceration	Derm			Acids/Alkalis, Arsenic trioxide, Bery...
Skeletal malformations	Peds	Develop	musculo-sk	Ethanol	Arsenic	Ethylene glycol ethers, Ethylene oxid...	Includes limb reduction, syndactyly, ...	58, 68, 89
Seizures	Neuro	Develop		Carbon monoxide, Cyanide, Lead, Methy...	Aluminum, Halogenated hydrocarbons, P...	Beryllium, Boron, Hexachlorophene, Or...		58, 60, 89, 98
Scrotal cancer	Onc	Derm	G.U.	Coal tar+, Shale oils+, PAHs	Creosotes#,		+ - Group 1 human carcinogen (IARC); ...
Scleroderma	Autoimm	Derm	Female	Silica	Solvents (including: aromatic mixes, ...	Estrogens, Epoxy resin, Herbicide, Me...	Occupational silica exposure has been...	9, 23, 77
Sarcoidosis	Resp	Auto-imm			Silica	Aluminum, Barium, Beryllium, Cobalt, ...
Salivary gland cancer	Onc	ENT		Ionizing radiation
Rhinitis - irritant	Resp	Imm	ENT	Aldehydes, Ammonia, Chlorine, Diesel ...			I117
Soft tissue sarcoma	Onc	Peds		Dioxins (TCDD+)	Chlorophenols^, DDT, Phenoxyacetic ac...	Cadmium, Captofol, Chromium, Cobalt, ...	Includes rhabdomyosarcoma, fibrosarco...	25, 26, 36, 84, 89, 98, 123
Spasticity/Myoc...	Neuro	Muscuol-sk.		Methyl mercury	Aluminum, Carbon monoxide, Hexane; Pe...	Bismuth		60, 98
Steatosis (fatty liver)	Hepat	G.I.		Carbon tetrachloride, Chloroform, Eth...	Arsenic, Halothane, Hydrazine, Hydroc...		Arsenical pesticides have been associ...	6, 47

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Disease and Chemical References (157)

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